How to use Buserelin

Unsure about self-administering IVF treatment medications? Does the thought of giving yourself injections make you feel anxious? There is no need to worry – help is at hand with our ‘Using Buserelin’ FAQs.

Drug teach support

Every new Bourn Hall patient is invited to attend a ‘drug teach’ support session as part of a nurse discussion appointment at one of our IVF fertility clinics – where you will be shown how to administer the medication. There’ll also be an opportunity for both you and your partner to ask questions.

To give you some extra help at home, we’ve put together a short video that shows you how to use the medication for down regulation – the first stage of the IVF treatment where drugs are used to suppress the menstrual cycle – Buserelin. It’s sometimes known by its brand name, Suprecur, and is administered by injection. The video below takes you through the injection process step by step.

There are additional, easy-to-follow instructions for using other drugs used in IVF treatment at

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Frequently Asked Questions

Suprecur is the brand name for the medication; Buserelin is the generic name. Buserelin is the first medicine you take on an IVF cycle, and is referred to as down regulation medication.

Buserelin puts you temporarily into a mini-menopausal state, so you may experience symptoms including hot flushes, night sweats, headaches and mood swings.

The bottle should be kept at below 25C in a safe, dry place. This can be in the fridge.

The expiry date is 15 days from when you first opened it. There is a space on the bottle to write this date to help you remember. Do not use it after 15 days.

One bottle will have at least 11 doses of medication; some may have the full 15 days’ worth. If it looks like you’re running out, please contact your IVF fertility clinic and we can supply you with a fresh bottle.

Every person’s cycle is different. It is likely that you will be injecting the down regulation medication for approximately two to four weeks, but your nurse will explain more.

Put it straight into the sharps bin. If you have finished using it because it has passed the expiry date, make sure that you’ve got a new bottle to replace it, should you need it.

We recommend that you carry out the injection between 6pm-8pm every day. When you start to take the stimulation medication in addition to Buserelin, this will mean two injections every day. However, you don’t need to administer both at the same time.

Yes, as long as your partner is confident and competent with the injection technique, they can help or inject you instead.

Approximately a week after starting the down regulation medication. Don’t worry if it’s a few days earlier or later than expected – everyone’s cycle is different. It is important, once you have bled, to continue with the Buserelin unless advised otherwise.

If you have started to bleed as expected while on Buserelin, your treatment will continue as planned. You may be asked to contact the nurses when you bleed, or only to contact them if you have not bled prior to the next phase; if that is the case, we may need to adjust your treatment plan.

You will be supplied with pre-injection wipes but you do not need to use them, as the tummy is generally considered a clean area for injection anyway. You may wish to use them to wipe the top of the bottle before each injection.

Once you have finished all of your injections – which will most likely be once you’ve had your trigger injection – close the sharps bin completely so it’s safe to transport and then bring it in with you to your next appointment.

Often with a frozen cycle, Buserelin is recommended prior to starting the oestrogen tablets, and for a little while afterwards. Your nurse coordinator will let you know what’s recommended for your treatment.


If you have any other concerns, just get in touch with the nurse coordinators at your IVF fertility clinic –they’ll be happy to talk you through any of your symptoms or answer any questions.